Rabbit Anti Cd8 Antibody Abcam

Mouse Monoclonal Anti-Human CD8 IgG

AB-14810 100 ug
EUR 416.4

Human IgG antibody Laboratories manufactures the rabbit anti cd8 antibody abcam reagents distributed by Genprice. The Rabbit Anti Cd8 Antibody Abcam reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact rabbit Antibody. Other Rabbit products are available in stock. Specificity: Rabbit Category: Anti Group: Cd8 Antibody

Mouse Monoclonal Anti-Human CD8-FITC IgG

100 ug
EUR 416.4

Mouse Monoclonal Anti-Human CD8-biotinylated IgG

100 ug
EUR 416.4

Anti-CD8 Antibody

100ul
EUR 189
Description: CD8 (cluster of differentiation 8) is a transmembrane glycoprotein that serves as a co-receptor for the T-cell receptor (TCR). Along with the TCR, the CD8 co-receptor plays a role in T cell signaling and aiding with cytotoxic T cell-antigen interactions. Like the TCR, CD8 binds to a major histocompatibility complex (MHC) molecule, but is specific for the MHC class I protein. There are two isoforms of the protein, alpha and beta, each encoded by a different gene. In humans, both genes are located on chromosome 2 in position 2p12. The CD8 co-receptor is predominantly expressed on the surface of cytotoxic T cells, but can also be found on natural killer cells, cortical thymocytes, and dendritic cells. The CD8 molecule is a marker for cytotoxic T cell population. It is expressed in T cell lymphoblastic lymphoma and hypo-pigmented mycosis fungoides. The extracellular IgV-like domain of CD8-α interacts with the α3 portion of the Class I MHC molecule. This affinity keeps the T cell receptor of the cytotoxic T cell and the target cell bound closely together during antigen-specific activation. Cytotoxic T cells with CD8 surface protein are called CD8+ T cells. The main recognition site is a flexible loop at the α3 domain of an MHC molecule. This was discovered by doing mutational analyses. The flexible α3 domain is located between residues 223 and 229 in the genome. In addition to aiding with cytotoxic T cell antigen interactions the CD8 co-receptor also plays a role in T cell signaling. The cytoplasmic tails of the CD8 co-receptor interact with Lck (lymphocyte-specific protein tyrosine kinase). Once the T cell receptor binds its specific antigen Lck phosphorylates the cytoplasmic CD3 and ζ-chains of the TCR complex which initiates a cascade of phosphorylation eventually leading to activation of transcription factors like NFAT, NF-κB, and AP-1 which affect the expression of certain genes.

Anti-CD8 Antibody

100ug/100ul
EUR 225
Description: Available in various conjugation types.

Anti-CD8 Antibody

100 µg
EUR 450

Anti-CD8 antibody

1 mL
EUR 294

Anti-CD8 antibody

100 µg
EUR 487.2

Cd8 Antibody information

Anti-CD8 alpha Antibody, Rabbit Polyclonal

MBS8111477-5x01mL 5x0.1mL
EUR 1200

Anti-CD8 alpha Antibody, Rabbit Polyclonal

MBS8111478-002mL 0.02mL
EUR 175

Anti-CD8 alpha Antibody, Rabbit Polyclonal

MBS8111478-01mL 0.1mL
EUR 320

Anti-CD8 alpha Antibody, Rabbit Polyclonal

MBS8111478-5x01mL 5x0.1mL
EUR 1300

Anti-CD8 alpha Antibody, Rabbit Polyclonal

MBS8112453-01mL 0.1mL
EUR 300

Anti-CD8 alpha Antibody, Rabbit Polyclonal

MBS8112453-5x01mL 5x0.1mL
EUR 1200

Anti-CD8 alpha Antibody, Rabbit Polyclonal

MBS8124183-01mL 0.1mL
EUR 300

Anti-CD8 alpha Antibody, Rabbit Polyclonal

MBS8124183-5x01mL 5x0.1mL
EUR 1200

Anti-CD8 alpha Rabbit Monoclonal Antibody

MBS179815-01mL 0.1mL
EUR 450

Anti-CD8 alpha Rabbit Monoclonal Antibody

MBS179815-5x01mL 5x0.1mL
EUR 1870

ABCA4 Rabbit anti-Human Polyclonal Antibody

MBS2403219-005mg 0.05mg
EUR 615

ABCA4 Rabbit anti-Human Polyclonal Antibody

MBS2403219-5x005mg 5x0.05mg
EUR 2605

ABCA7 Rabbit anti-Human Polyclonal Antibody

MBS2403220-005mg 0.05mg
EUR 615

ABCA7 Rabbit anti-Human Polyclonal Antibody

MBS2403220-5x005mg 5x0.05mg
EUR 2605

MOUSE ANTI RABBIT CD8

MBS224404-01mg 0.1mg
EUR 390

MOUSE ANTI RABBIT CD8

MBS224404-5x01mg 5x0.1mg
EUR 1570

Rabbit Anti-Mouse CD8 alpha monoclonal antibody, clone S127

CABT-ZB480 50 μl
EUR 520
Description: Rabbit